In the ever-evolving world of fitness and wellness, the quest for effective weight loss solutions has led many individuals to explore a variety of methods. Dietary supplements have become a tempting option for individuals seeking a "magic bullet" solution to combat obesity. The supplements for weight loss work by breaking down fats and preventing the formation of new fats in the body. Among these, a category known as "fat burners" has gained considerable attention. These supplements, readily available in the market, claim to facilitate weight loss and diminish fat accumulation by either stimulating lipolysis or inhibiting lipogenesis. The key ingredients in these tablets may include stimulants, appetite suppressants, thermogenic, and other compounds believed to contribute to weight loss. These supplements claim to boost metabolism, increase energy levels, and accelerate the fat-burning process. However, before diving into the world of fat-burning tablets, it's crucial to understand the science behind these products and the potential risks involved. The efficacy and safety of these ingredients can vary widely, and it's essential to scrutinize them before you use them.
Understanding Fat-Burning Tablets
Let us understand the Fat burning tablets in detail. The term "fat burner," also known as "fat blockers" or "weight loss pills," refers to dietary supplements that reduce fat absorption, facilitate weight loss, enhance fat oxidation during exercise, or cause other long-term changes that stimulate fat metabolism (Jeukendrup and Randell, 2011). A good fat burner must burn the stored fats, break down and mobilize the fat cells, increase the metabolic rate, and inhibit the enlargement of fat cells (Nawrot et al ., 2013). However, it is important to emphasize that a fat burner should not replace a well-rounded diet and exercise plan. To enhance metabolism and activate fat-burning capabilities, the recommended approach is to incorporate thermogenic foods, stay hydrated, and engage in regular exercise.
Some lean body enhancers include:
- Chitosan, derived from the shells of crustaceans like crabs and lobsters, is a non-digestible fiber commonly used into supplements such as Chitosan-C and Chitorich (Galitzky et al., 2012). Functioning as an effective fat binder, it enters the body, binds to dietary fat, and prevents its absorption. While recommended for lowering cholesterol levels and promoting weight loss (Pooyandjoo et al., 2016; Vincent et al., 2003), this approach has some drawbacks, like interference with nutrient absorption and stomach pain, anal leakage, and diarrhea.
- L-carnitine, synthesized from amino acids, catalyzes transporting fatty acids into mitochondria during the breakdown of fats for metabolic energy. Widely available as a nutritional supplement, it plays a crucial role in maintaining a healthy body weight (Anton et al., 2008).
- Caffeine, found in coffee, tea, soft drinks, cocoa, and cola nut is the most widely used as an energy enhancer and fat loss supplement (Greer et al ., 2000). Research indicates that caffeine has the capacity to augment the release of stored fat and elevate the rate of calorie burning. Caffeine promotes fat loss at two major sites: fat cells and muscle cells.
- Green tea extract contains catechin epigallocatechin-3-gallate (EGCG), the active ingredient (Cabrera et al., 2006) that boost the metabolic rate by helping the body to burn more calories. A study examining the impact of green tea on weight loss among obese individuals indicated that the group following diet plan with green tea experienced a greater reduction in body fat compared to the placebo group (Hofman et al., 2008; Ha & Zemel, 2011).
- Conjugated Linoleic Acid (CLA) are identified by researchers for its role in encouraging fat breakdown (Millan et al., 2012). It transports dietary fat into cells for energy use or muscle building (Brenot et al., 2015).
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Garcinia cambogia, derived from a tropical fruit, gained popularity for its purported ability to inhibit fat production and curb appetite. However, scientific evidence supporting these claims is limited, and some studies have raised concerns about its safety. Before incorporating this ingredient into your regimen, it's crucial to consult with a healthcare professional.
- Fucoxanthin, derived from brown seaweed and various algae, is claimed to help in weight loss by increasing calorie expenditure and reducing fat accumulation. Initial studies suggest that fucoxanthin is generally safe when consumed at a dosage of 2.4 mg per day over a 16-week period. However, further exploration is necessary to ascertain its effectiveness and safety conclusively.
- Chromium is a mineral necessary for regulating blood sugar levels. Some studies suggest that it can boost muscle mass, help in fat loss, and reduce appetite and food intake. Chromium, found in food and supplements, is generally safe when consumed within recommended doses, ranging from 20 to 45 micrograms daily for adults. However, excessive amounts of chromium may lead to side effects such as watery stools, headaches, weakness, nausea, vomiting, constipation and dizziness.
If you're considering trying fat-burning tablets, it's important to approach their use with caution and follow these guidelines:
- Consult a Nutritionist/Healthcare Professional: Before incorporating any weight loss supplement into your routine, consult with a healthcare professional. They can assess your individual health status, provide personalized advice, and help you determine if these supplements are suitable for you.
- Read Labels Carefully: Thoroughly examine the ingredients list on fat-burning tablet labels. Be aware of any potential allergens or ingredients that may interact with medications you are currently taking.
- Moderate Your Expectations: Fat-burning tablets are not a magic solution for weight loss. They should be viewed as part of a comprehensive approach that includes a balanced diet and regular physical activity.
- Stay Hydrated: Some fat-burning tablets may have diuretic effects, leading to increased fluid loss. It's crucial to stay well-hydrated to counteract potential dehydration.
Fat-burning supplements typically contain multiple components (vitamins, minerals, fiber, caffeine, herbs, and plant extracts), each with its distinct mechanism of action. Evaluating the effectiveness of dietary supplements is challenging, However, when combined with a lifestyle program, weight management supplements can lead to 3% to 12% greater weight loss, providing health benefits like improved blood sugar and pressure. But caution is to be taken with fat burning pills, as they may lead to appetite loss, rapid initial weight loss, and potential risks like headaches and anxiety.
References -
1. Anton, S. D., Morrison, C. D., Cefalu, W. T. 2008. Effects of chromium picolinate on food intake and satiety. Diabetes Technol Ther, 10 (5): 405–412.
2. Bobyleva, V., Bellei, M., Kneer, N., Lardy, H. 2007. The effects of the ergosteroid 7-oxo-dehydroepiandrosterone on mitochondrial membrane potential: possible relationship to thermogenesis. Arch Biochem Biophys, 341 (1): 122–128
3. Boirie, M., Dangin, Y., Guillet, C., Beaufrere, B. 2011. Influence of the protein digestion rate on protein turnover in young and elderly subjects. J Nutr, 132 (10): 3228S–3233S
4. Bredsdorff, L., Wedebye, E. B., Nikolov, N. G., Hallas-Moller, T., Pilegaard, K. 2015. Raspberry ketone in food supplements–high intake, few toxicity data–a cause for safety concern? Regul Toxicol Pharmacol, 73: 196–200.
5. Brenot, F., Abenhaim, L., Moride, Y., Rich, S., Benichou, J., Kurz, X., et al. 2015. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med, 335: 609.
6. Cabrera, C., Artacho, R., Giménez, R. 2006. Beneficial effects of green tea; a review. J Am Coll Nutr, 25 (2): 79–99
7. Clapham, J. C., Arch, J. R. 2007. Thermogenic and metabolic antiobesity drugs: rationale and opportunities. Diabetes Obes Metab, 9: 259–275.
8. El-Zayat, S. R., Sibaii, H. & El-Shamy, K. A. 2019. Physiological process of fat loss. Bull Natl Res Cent, 43: 208.
9. Greer, F., Friars, D., Graham, T. E. 2000. Comparison of caffeine, theophylline ingestion: exercise metabolism and endurance. J Appl Physiol, 89 (5): 1837–1844.
10. Jeukendrup, A. E., & Randell, R. 2011. Fat burners: nutrition supplements that increase fat metabolism. Obesity reviews, 12 (10): 841-851.
11. Kersten, S. 2001. Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep, 2 (4): 282–286.
12. Kim, J., Park, J., & Lim, K. 2016. Nutrition supplements to stimulate lipolysis: a review in relation to endurance exercise capacity. J. Nutr. Sci. & Vitaminology, 62 (3): 141-161.
13. Klein S, Peters J, Holland B. Wolfe R. 2006. Effect of short- and long-term beta-adrenergic blockade on lipolysis during fasting in humans. Am J Physiol., 257: E65–E73.
14. Nawrot, P., Jordan, S., Leonard, S. 2013. Effects of caffeine on human health. Food Addit Contam., 20 (1):1–30
15. NIH: “Dietary Supplements for Weight Loss.” https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/
16. NIH: https://ods.od.nih.gov/factsheets/WeightLoss-Consumer/
17. Onakpoya, I. J., Posadzki, P. P., Watson, L. K., Davies, L. A., Ernst, E. 2012. The efficacy of long-term conjugated linoleic acid (CLA) supplementation on body composition in overweight and obese individuals: a systematic review and meta-analysis of randomized clinical trials. Eur J. Nutr., 51 (2): 127–134.
18. Rao N, Spiller HA, Hodges NL, Chounthirath T, Casavant MJ, Kamboj AK et al. 2017. An increase in dietary supplement exposures reported to US poison control centers. J Med Toxicol, 24 (4): 56–68
19. Shekelle, P. G., Hardy, M. L., Morton, S. C., Maglione, M., Mojica, W. A., Suttorp, M. J., Rhodes, S. L., Jungvig, L., Gagne, J. 2003. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance. JAMA, 289 (12): 1537–1545.
20. Watanabe, M., Risi, R., Masi, D., Caputi, A., Balena, A., Rossini, G., Tuccinardi, D., Mariani, S., Basciani, S., Manfrini, S., Gnessi, L., & Lubrano, C. 2020. Current Evidence to Propose Different Food Supplements for Weight Loss: A Comprehensive Review. Nutrients, 12 (9): 2873.
