Women's Health | Women Understanding endocrine system disruptors and how environmental toxins affect women's hormonal health | Healthyr U
Author Avatar

Misbah Wasi

Functional Nutrition Specialist, Scientific & Regulatory Advisor for Health Supplements

Misbah Wasi is a seasoned professional in the field of Nutrition Science and Food Regulation for over 15 years. Currently, she is lendin her expertise in the area of Health Supplements and Nutraceuticals and is an active member of the Standards Review Group (SRG) - Nutraceuticals FSSAI Ms. Wasi is a post-graduate in Food and Nutrition. Certified Lead Food Safety Management Systems Auditor (FSMS, FSSC 22000) and a certified FoSTaC traine for Health Supplements and Nutraceuticals. She is also a Subject Matter Expert for ‘Food Regulations in India’ for IFLR (International Food Laws and Regulations) course at Michigan State University.

How Environmental Toxins Affect Women's Hormones

Hormonal balance plays a crucial role in women's health, affecting everything from mood and metabolism to reproductive health and energy levels. However, modern lifestyles expose women to numerous environmental toxins that interfere with the body's natural hormone regulation. These toxins, also known as endocrine system disruptors, can lead to hormonal disruption, causing various women’s health problems like irregular periods, fertility challenges, mood swings, and metabolic disorders.


From plastics and pesticides to household cleaning products and personal care items, endocrine-disrupting chemicals (EDCs) are everywhere. 


The good news? By identifying these environmental toxicants and making informed choices, you can reduce your toxin burden and support healthy hormones.

 


Understanding Hormones and Their Role in
Women's Health

Hormones are chemical messengers that regulate vital functions in the body, including metabolism, mood, reproduction, and immune health. The endocrine system is responsible for producing and balancing these hormones. However, exposure to endocrine system disruptors can interfere with this process, leading to hormonal disruption and a wide range of hormone problems(1).


Common Symptoms of Hormonal Disruption in Women

• Irregular menstrual cycles or heavy periods

• Unexplained weight gain or difficulty losing weight

• Persistent fatigue and low energy

• Mood swings, anxiety, or depression

• Acne, hair thinning, or excessive hair growth

• Fertility struggles or PCOS (polycystic ovary syndrome) like symptoms

• Sleep disturbances and low libido


If you are experiencing any of these effects of hormonal imbalance, environmental toxins may be playing a role.


Environmental toxins
, also known as endocrine system disruptors, can mimic, block, or alter the natural functions of hormones, leading to hormonal disruption. EDCs interfere with the endocrine system, affecting the body’s ability to regulate reproductive health, metabolism, mood, and overall hormonal health. Over time, exposure to these environmental toxicants increases the toxin burden, leading to hormone problems in women.


Let’s break down how specific environmental toxins impact women’s hormonal health and contribute to common women’s health problems.


1. Endocrine Disrupting Chemicals Mimic or Block Hormones

Some endocrine-disrupting chemicals behave like natural hormones, especially oestrogen and confuse the body’s endocrine system. This leads to hormonal disruption, throwing off the delicate balance between oestrogen, progesterone, and other hormones.


Effects of Hormone Mimicry or Blockage:

Oestrogen Dominance:

• Chemicals like BPA, phthalates, and parabens act like synthetic oestrogen in the body, leading to an overload of oestrogen(2). This increases the risk of irregular periods, bloating, mood swings, and breast tenderness. Long-term exposure to these chemicals has been linked to PCOS, fibroids, and endometriosis.


Reduced Fertility:

• EDCs interfere with progesterone, a key hormone needed for ovulation and maintaining pregnancy. This imbalance can cause difficulty conceiving, miscarriages, and irregular ovulation(3).


Thyroid Dysfunction:

• Some environmental toxicants, like flame retardants and pesticides, interfere with the thyroid’s ability to produce hormones. This can lead to hypothyroidism, slow metabolism, weight gain, and fatigue(4).


2. Heavy Metals Interfere with Hormone Production

Exposure to heavy metals like lead, mercury, and cadmium disrupts the body's natural ability to regulate healthy hormones. These metals accumulate in the body over time, increasing the toxin burden and contributing to long-term hormone problems.


Effects of Heavy Metal Toxicity on Hormones:

Thyroid Imbalance:

• Mercury and lead interfere with the thyroid’s ability to produce T3 and T4 hormones, essential for metabolism(5,6). Low thyroid function can cause weight gain, brain fog, hair thinning, and chronic fatigue.


Increased Inflammation and PMS Symptoms:

• Heavy metals contribute to chronic inflammation, worsening PMS, cramps, and menstrual cycle irregularities. They can also trigger autoimmune disorders, which impact hormonal health(7).


Disrupted Menstrual Cycle:

Lead exposure has been linked to shorter menstrual cycles and irregular periods, affecting overall reproductive health(8).


3. Pesticides and Herbicides Disrupt Oestrogen and Thyroid Hormones

Pesticides and herbicides used in conventional farming contain endocrine system disruptors that interfere with hormone function. These environmental toxicants are absorbed through food, air, and water, leading to hormonal disruption.


Effects of Pesticides on Hormonal Health:

Irregular Menstrual Cycles and Early Menopause:

• Exposure to glyphosate (a common herbicide) has been linked to changes in menstrual cycle length and early menopause. Women exposed to high levels of pesticides may experience more severe PMS and hormonal acne(9).


Thyroid Dysfunction:

• Pesticides have been found to inhibit thyroid function, leading to symptoms like fatigue, slow metabolism, and mood changes. Hypothyroidism caused by pesticide exposure is associated with weight gain and difficulty concentrating(10).


Increased Risk of Breast Cancer:

• Some pesticides mimic oestrogen, increasing the risk of hormone-sensitive cancers like breast cancer(11). Women with high pesticide exposure may experience breast tenderness, fibroids, or cysts.


4. Synthetic Fragrances and Plastics Increase Toxin Burden

Perfumes, air fresheners, candles, and even household cleaning products contain phthalates and parabens, which act as endocrine system disruptors. These chemicals contribute to hormonal disruption by affecting oestrogen and progesterone balance.


Effects of Synthetic Fragrances and Plastics on Hormonal Health:


Disrupts Oestrogen and Progesterone Levels:

• Phthalates mimic oestrogen, leading to irregular menstrual cycles, increased PMS, and mood swings. Long-term exposure has been linked to low fertility and PCOS(12).


Thyroid Hormone Disruption:

• Plastics contain BPA, which interferes with thyroid function, leading to weight fluctuations, fatigue, and hair thinning(13).


Increased Risk of Hormone-Sensitive Cancers:

• Parabens have been detected in breast tissue samples, suggesting a possible link to breast cancer(14).


5. Household Cleaners Contain Hormone-Disrupting Chemicals

Many conventional household cleaning products contain environmental toxicants that can interfere with hormone balance. Ingredients like triclosan, ammonia, and chlorine can lower oestrogen levels and affect the thyroid.


Effects of Cleaning Chemicals on Hormones:

Triclosan Lowers oestrogen and Disrupts Menstrual Cycles:

• Found in antibacterial soaps and hand sanitizers, triclosan has been linked to lower oestrogen levels and irregular periods(15).


Increased Risk of Endocrine Disorders:

• Regular exposure to toxic cleaning chemicals can lead to hormonal imbalances, increasing the risk of infertility, PCOS, and chronic fatigue.


Tips to Reduce Toxin Burden and Support Hormone Balance

Here are effective ways to reduce toxin burden and promote healthy hormones naturally:


1. Eat a Hormone-Supportive Diet

• Include cruciferous vegetables (broccoli, kale, cauliflower) to support oestrogen detoxification.

• Choose healthy fats like avocados, nuts, and olive oil for hormone production.

• Consume fiber-rich foods to eliminate excess oestrogen.(18)


2. Filter Your Water

• Use a high-quality water filter to remove environmental toxicants like chlorine, fluoride, and heavy metals.

• Avoid plastic bottled water, as it may contain endocrine system disruptors like BPA.


3. Choose Natural Skincare and Cleaning Products

• Look for paraben-free, fragrance-free personal care products.

• Use essential oils instead of synthetic air fresheners.

• Switch to eco-friendly cleaning products to limit exposure to harmful chemicals.


4. Sweat Out Toxins Through Exercise and Sauna Therapy

• Regular movement and exercise help detoxify excess hormones.

• Saunas may aid in heavy metal detoxification, reducing toxin burden.(16)


5. Support Liver Health for Better Hormone Balance

• The liver helps eliminate toxins that interfere with hormone and health.

• Drink lemon water and consume milk thistle to support liver function.(17)


6. Reduce Plastic Use and Heat Exposure

• Never microwave food in plastic containers, as heat releases endocrine-disrupting chemicals.

• Store food in glass or stainless steel containers.


7. Prioritize Sleep and Stress Management

• Poor sleep increases hormone problems, worsening imbalances.

• Reduce stress levels, as chronic stress raises cortisol, which interferes with hormonal health.


Final Thoughts 

Environmental toxins are everywhere, but you don’t have to let them take control of your hormone and health. By making small but powerful lifestyle changes, switching to cleaner products, eating hormone-supportive foods, and reducing toxin burden, you can promote healthy hormones and prevent hormonal disruption.


If you’re struggling with the effects of hormonal imbalance, these steps can help restore hormone balance naturally. Take control of your hormonal health today and create a toxin-free environment that supports overall women’s health and well-being!


References

  1. Piazza, M. J., & Urbanetz, A. A. (2019). Environmental toxins and the impact of other endocrine disrupting chemicals in women’s reproductive health. JBRA. https://doi.org/10.5935/1518-0557.20190016

  2. Gao, H., Yang, B., Li, N., Feng, L., Shi, X., Zhao, W., & Liu, S. (2015). Bisphenol A and Hormone-Associated cancers. Medicine, 94(1), e211. https://doi.org/10.1097/md.0000000000000211

  3. Vessa, B., Perlman, B., McGovern, P. G., & Morelli, S. S. (2022). Endocrine disruptors and female fertility: a review of pesticide and plasticizer effects. F&S Reports, 3(2), 86–90. https://doi.org/10.1016/j.xfre.2022.04.003

  4. Leemans, M., Couderq, S., Demeneix, B., & Fini, J. (2019). Pesticides with Potential Thyroid Hormone-Disrupting Effects: A Review of Recent data. Frontiers in Endocrinology, 10. https://doi.org/10.3389/fendo.2019.00743

  5. Pamphlett, R., Doble, P. A., & Bishop, D. P. (2021). Mercury in the human thyroid gland: Potential implications for thyroid cancer, autoimmune thyroiditis, and hypothyroidism. PLoS ONE, 16(2), e0246748. https://doi.org/10.1371/journal.pone.0246748

  6. Rivera-Buse, J. E., Patajalo-Villalta, S. J., Donadi, E. A., Barbosa, F., Magalhães, P. K. R., & Maciel, L. M. Z. (2023). Impact of lead exposure on the thyroid glands of individuals living in high- or low-lead exposure areas. Medicine, 102(12), e33292. https://doi.org/10.1097/md.0000000000033292

  7. Park, J., Lee, J. J., Park, S., Lee, H., Nam, S., Lee, S., & Lee, H. (2022). Endocrine Disrupting Chemicals and Premenstrual syndrome in female college students in East Asia: a Multi-Country study. International Journal of Women S Health, Volume 14, 167–177. https://doi.org/10.2147/ijwh.s349172

  8. Pollack, A. Z., Schisterman, E. F., Goldman, L. R., Mumford, S. L., Albert, P. S., Jones, R. L., & Wactawski-Wende, J. (2011). Cadmium, lead, and mercury in relation to reproductive hormones and anovulation in premenopausal women. Environmental Health Perspectives, 119(8), 1156–1161. https://doi.org/10.1289/ehp.1003284

  9. Bretveld, R. W., Thomas, C. M., Scheepers, P. T., Zielhuis, G. A., & Roeleveld, N. (2006). Pesticide exposure: the hormonal function of the female reproductive system disrupted? Reproductive Biology and Endocrinology, 4(1). https://doi.org/10.1186/1477-7827-4-30

  10. Goldner, W. S., Sandler, D. P., Yu, F., Hoppin, J. A., Kamel, F., & LeVan, T. D. (2010). Pesticide use and thyroid disease among women in the Agricultural Health study. American Journal of Epidemiology, 171(4), 455–464. https://doi.org/10.1093/aje/kwp404

  11. Panis, C., & Lemos, B. (2024). Pesticide exposure and increased breast cancer risk in women population studies. The Science of the Total Environment, 933, 172988. https://doi.org/10.1016/j.scitotenv.2024.172988

  12. Chen, X., Xu, S., Tan, T., Lee, S., Cheng, S., Lee, F., Xu, S., & Ho, K. (2014). Toxicity and estrogenic endocrine disrupting activity of phthalates and their mixtures. International Journal of Environmental Research and Public Health, 11(3), 3156–3168. https://doi.org/10.3390/ijerph110303156

  13. Kim, M. J., & Park, Y. J. (2019). Bisphenols and thyroid hormone. Endocrinology and Metabolism, 34(4), 340. https://doi.org/10.3803/enm.2019.34.4.340

  14. Hager, E., Chen, J., & Zhao, L. (2022). MiniReview: Parabens exposure and breast cancer. International Journal of Environmental Research and Public Health, 19(3), 1873. https://doi.org/10.3390/ijerph19031873

  15. Zhu, W., Zhou, W., Huo, X., Zhao, S., Gan, Y., Wang, B., Cheng, W., Ouyang, F., Wang, W., Tian, Y., & Zhang, J. (2019). Triclosan and female reproductive health. Epidemiology, 30(Supplement 1), S24–S31. https://doi.org/10.1097/ede.0000000000001011

  16. Sears ME, Kerr KJ, Bray RI. Arsenic, cadmium, lead, and mercury in sweat: a systematic review. J Environ Public Health. 2012;2012:184745. doi: 10.1155/2012/184745. Epub 2012 Feb 22. PMID: 22505948; PMCID: PMC3312275.

  17. Hobbs C. Natural Therapy for Your Liver: Herbs and Other Natural Remedies for a Healthy Liver. Penguin; 2002 Sep 16.

  18. Rose DP, Goldman M, Connolly JM, Strong LE. High-fiber diet reduces serum estrogen concentrations in premenopausal women. Am J Clin Nutr. 1991 Sep;54(3):520-5. doi: 10.1093/ajcn/54.3.520. PMID: 1652197.
Back to blog